Best Midsize Luxury Sedans 2025 Reviews. The three best luxury midsize cars are the 2024 audi a6, 2025 genesis g80, and the 2025 lexus es hybrid which all have an overall score of 8.9 out of 10. Find the best car for your needs today!

The 5 series continues to set the standard in the. Luxury midsize cars offer a perfect blend of comfort, performance, and prestige.